Research
Cellular
OSM acts on adipocytes to induce the expression and secretion of plasminogen activator inhibitor 1 and IL-6.
Understanding OSM's role could help in developing strategies to modulate inflammation in obesity.
StrongSupportsmedium confidence
OSM acts on adipocytes to induce the expression and secretion of plasminogen activator inhibitor 1 and IL-6.
Why this rating
Direct effects observed in murine adipocytes provide strong evidence.
Source
Oncostatin M Is Produced in Adipose Tissue and Is Regulated in Conditions of Obesity and Type 2 Diabetes
David Sánchez‐Infantes et al. · The Journal of Clinical Endocrinology & Metabolism · 2013
DOI 10.1210/jc.2013-3555
otherCited 80×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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