Research
Cellular
A novel combination of common variants of HRAS1, LASS1, and APOE is associated with human lifespan and healthy aging.
Practitioners may consider the genetic profiles of HRAS1, LASS1, and APOE when assessing longevity and healthy aging.
StrongSupportsmedium confidence
We have identified a novel combination of common variants of three genes that has a marked association with human lifespan and healthy aging.
Why this rating
The study involves haplotype analysis and replication in a second population.
Source
<i>HRAS1</i> and <i>LASS1</i> with <i>APOE</i> are associated with human longevity and healthy aging
S. Michal Jazwinski et al. · Aging Cell · 2010
DOI 10.1111/j.1474-9726.2010.00600.x
otherCited 67×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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