Research
Metabolic adaptation
Leptin-treated subjects had higher fat oxidation than controls after weight loss.
Leptin replacement may enhance fat oxidation in patients with congenital leptin deficiency after weight loss.
StrongSupportsmedium confidence
After weight loss, leptin-treated subjects had higher fat oxidation than controls (P = 0.005).
Why this rating
Based on study design from abstract.
Source
Leptin Replacement Prevents Weight Loss-Induced Metabolic Adaptation in Congenital Leptin-Deficient Patients
José E. Galgani et al. · The Journal of Clinical Endocrinology & Metabolism · 2010
cohort · n=6Cited 59×
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