Research
Cellular
Aging and muscle disuse lead to the development of anabolic resistance and contribute to the loss of skeletal muscle mass.
Awareness of anabolic resistance is crucial for designing interventions for older adults or those with muscle disuse.
StrongSupportsmedium confidence
Conversely, aging (sarcopenia) and muscle disuse lead to the development of anabolic resistance and contribute to the loss of skeletal muscle mass.
Why this rating
The claim is supported by established knowledge in the field.
Source
Resistance Exercise, Aging, Disuse, and Muscle Protein Metabolism
James McKendry et al. · Comprehensive physiology · 2021
DOI 10.1002/cphy.c200029
reviewCited 57×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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