Research
Metabolic adaptation
The obesity paradox was observed among people with type 2 diabetes, with an adjusted hazard ratio for obese vs. normal BMI of 0.78 (95% CI 0.65, 0.95).
Healthcare providers should consider the implications of obesity on mortality in patients with type 2 diabetes.
StrongSupportsmedium confidence
For BMI, the obesity paradox was observed among people with type 2 diabetes (adjusted hazard ratio for obese vs. normal BMI 0.78 [95% CI 0.65, 0.95]).
Why this rating
Based on the large cohort study design from the abstract.
Source
Adiposity-Mortality Relationships in Type 2 Diabetes, Coronary Heart Disease, and Cancer Subgroups in the UK Biobank, and Their Modification by Smoking
David Jenkins et al. · Diabetes Care · 2018
cohort · n=45790Cited 55×
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