Research
Metabolic adaptation
Smoking status consistently modified the adiposity-mortality relationship.
Practitioners should consider smoking status when evaluating the risks associated with obesity.
StrongSupportsmedium confidence
The obesity paradox was pronounced in current smokers, absent in never smokers, and more pronounced in men than in women.
Why this rating
Based on the large cohort study design from the abstract.
Source
Adiposity-Mortality Relationships in Type 2 Diabetes, Coronary Heart Disease, and Cancer Subgroups in the UK Biobank, and Their Modification by Smoking
David Jenkins et al. · Diabetes Care · 2018
cohort · n=45790Cited 55×
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