Research
Molecular
Carnitine and butyrobetaine are each associated with a 26% increased risk of death from any cause among older adults.
Practitioners should be aware of the potential risks associated with elevated levels of carnitine and butyrobetaine in older adults.
StrongSupportsmedium confidence
The hazard ratios for death from any cause... were 1.26 (95% CI, 1.15-1.40) for carnitine, and 1.26 (95% CI, 1.13-1.40) for butyrobetaine.
Why this rating
Based on a large prospective cohort study design.
Source
Association of Trimethylamine <i>N</i>-Oxide and Metabolites With Mortality in Older Adults
Amanda M. Fretts et al. · JAMA Network Open · 2022
cohort · n=5333Cited 51×
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