Research

Metabolic adaptation

Increasing polyunsaturated fat intake in place of carbohydrates is associated with a lower risk of type 2 diabetes (hazard ratio 0.90 per 5% of energy).

Replacing carbohydrates with polyunsaturated fats may reduce the risk of type 2 diabetes.

StrongSupportsmedium confidence
The increase of polyunsaturated fat and total omega 6 polyunsaturated fat intake in place of carbohydrate was associated with a lower risk of type 2 diabetes, with hazard ratios of 0.90 (0.82 to 0.98, I 2 =18.0%, τ 2 =0.006; per 5% of energy).
Jordi Merino et al. · BMJ · 2019

Why this rating

Based on a meta-analysis of individual participant data.

Source

Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis

Jordi Merino et al. · BMJ · 2019

Meta-analysisCited 48×
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