Research
Metabolic adaptation
Increasing monounsaturated fat intake in place of carbohydrates is associated with a higher risk of type 2 diabetes (hazard ratio 1.10 per 5% of energy).
Increasing monounsaturated fats instead of carbohydrates may elevate the risk of type 2 diabetes.
StrongSupportsmedium confidence
Increasing monounsaturated fat in place of carbohydrate was associated with a higher risk of type 2 diabetes (hazard ratio 1.10, 95% confidence interval 1.01 to 1.19, I 2 =25.9%, τ 2 =0.006; per 5% of energy).
Why this rating
Based on a meta-analysis of individual participant data.
Source
Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis
Jordi Merino et al. · BMJ · 2019
Meta-analysisCited 48×
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