Research
Neural
RT performed to set failure likely exacerbates neuromuscular fatigue, muscle damage, and perceived discomfort compared to non-failure RT.
Practitioners should be cautious of the increased fatigue and discomfort associated with set failure training.
StrongSupportsmedium confidence
RT performed to set failure likely induces greater neuromuscular fatigue, muscle damage, and perceived discomfort than non-failure RT.
Why this rating
The claim is based on a scoping review of existing literature.
Source
Towards an improved understanding of proximity-to-failure in resistance training and its influence on skeletal muscle hypertrophy, neuromuscular fatigue, muscle damage, and perceived discomfort: A scoping review
Martin C. Refalo et al. · Journal of Sports Sciences · 2022
DOI 10.1080/02640414.2022.2080165
reviewCited 43×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
Related findings · Neural
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →