Research
Cellular
Women with PCOS exhibited approximately 80% lower expression of perilipins PLIN1, PLIN3, and PLIN5 compared to controls.
Women with PCOS may have impaired lipolysis due to lower perilipin expression.
StrongSupportsmedium confidence
The expression of PLIN1, PLIN3, and PLIN5... was ∼ 80% lower in women with PCOS (all P<0.05).
Why this rating
Based on study design from abstract.
Source
Potential effects of aerobic exercise on the expression of perilipin 3 in the adipose tissue of women with polycystic ovary syndrome: a pilot study
Jeffrey D. Covington et al. · European Journal of Endocrinology · 2014
DOI 10.1530/eje-14-0492
cross-sectional · n=16Cited 27×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- The expression of perilipin 3 (PLIN3) significantly increased following 16 weeks of aerobic exercise training in women with polycystic ovary syndrome (PCOS).Strong
- Following aerobic exercise training, in vitro adipose oleate oxidation, glycerol secretion, and PLIN3 protein expression were increased in women with PCOS.Strong
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