Research
Cellular
Aging and muscle disuse lead to the development of anabolic resistance and contribute to the loss of skeletal muscle mass.
Awareness of the effects of aging and disuse on muscle mass is crucial for intervention strategies.
StrongSupportsmedium confidence
Conversely, aging (sarcopenia) and muscle disuse lead to the development of anabolic resistance and contribute to the loss of skeletal muscle mass.
Why this rating
The claim is supported by a synthesis of existing research.
Source
Resistance Exercise, Aging, Disuse, and Muscle Protein Metabolism
James McKendry et al. · Comprehensive physiology · 2021
DOI 10.1002/j.2040-4603.2021.tb00179.x
reviewCited 23×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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