Research
Cellular
High-dose leucine supplementation did not enhance gains in muscle strength after a 12-week resistance training program.
Practitioners should consider that leucine supplementation may not provide additional benefits for muscle strength in adequately protein-fed individuals.
StrongRefutesmedium confidence
High-dose leucine supplementation did not enhance gains in muscle strength and mass after a 12-wk RT program in young resistance-trained males consuming adequate amounts of dietary protein.
Why this rating
Based on study design from abstract.
Source
Leucine Supplementation Has No Further Effect on Training-induced Muscle Adaptations
Isabel Thomazi de Andrade et al. · Medicine & Science in Sports & Exercise · 2020
DOI 10.1249/mss.0000000000002307
rct · n=25Cited 22×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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