Research
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Semaglutide did not increase or reduce the risk of eye disorders (OR, 1.01; 95% CI, 0.91-1.12) or diabetic retinopathy (OR, 1.04; 95% CI, 0.92-1.17).
Semaglutide can be considered safe regarding eye disorders and diabetic retinopathy.
StrongRefutesmedium confidence
Semaglutide did not increase or reduce the risk of eye disorders (OR, 1.01; 95% CI, 0.91-1.12) or diabetic retinopathy (OR, 1.04; 95% CI, 0.92-1.17).
Why this rating
Based on a comprehensive analysis of 78 trials.
Source
Ocular Adverse Events With Semaglutide
Gabriella Richter da Natividade et al. · JAMA Ophthalmology · 2025
DOI 10.1001/jamaophthalmol.2025.2489
Meta-analysisCited 22×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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