Research
Cellular
Tirzepatide treatment significantly decreased Alt-Ext-induced IL-5 and IL-13 levels in lung homogenates compared with vehicle treatment.
Tirzepatide may help reduce allergic inflammation in obese asthma patients.
StrongSupportsmedium confidence
Alt-Ext-induced IL-5 and IL-13 were significantly decreased in the tirzepatide treatment group compared with the vehicle treatment group.
Why this rating
Based on direct measurement of inflammatory markers.
Source
Dual GIPR and GLP‐1R agonist tirzepatide inhibits aeroallergen‐induced allergic airway inflammation in mouse model of obese asthma
Shinji Toki et al. · Clinical & Experimental Allergy · 2022
DOI 10.1111/cea.14252
otherCited 16×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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