Research
Molecular
Fifteen distinct gene clusters are regulated by disuse and connected to muscle mass or MPS changes.
Understanding these gene clusters may help in developing interventions to mitigate muscle loss during disuse.
StrongSupportsmedium confidence
Application of weighted gene co‐expression network analysis identified 15 distinct gene clusters (“modules”) with an expression profile regulated by disuse and/or quantitatively connected to disuse‐induced muscle mass or MPS changes.
Why this rating
Based on the robust analysis of gene expression.
Source
Transcriptomic links to muscle mass loss and declines in cumulative muscle protein synthesis during short‐term disuse in healthy younger humans
Craig R. G. Willis et al. · The FASEB Journal · 2021
other · n=8Cited 14×
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