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Rapid weight loss induced by semaglutide can lead to noticeable facial volume loss and the appearance of a prematurely aged face, referred to as 'Ozempic face.'

Healthcare providers should be aware of the potential cosmetic implications of semaglutide use for weight loss.

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However, rapid weight loss induced by semaglutide has been shown to lead to noticeable facial volume loss and the appearance of a prematurely aged face referred to as 'Ozempic face.'
Karen Montecinos et al. · Dermatological Reviews · 2024

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The claims are based on a comprehensive review of existing literature.

Source

Semaglutide “Ozempic” Face and Implications in Cosmetic Dermatology

Karen Montecinos et al. · Dermatological Reviews · 2024

DOI 10.1002/der2.70003

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DOI resolved against Crossref · corpus check 2026-06-10

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