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Insulin monotherapy for T2DM treatment increases the risk of major CV events and deaths from HF compared to metformin.

Practitioners should be cautious when prescribing insulin monotherapy for type 2 diabetes due to increased cardiovascular risks.

StrongRefutesmedium confidence
insulin monotherapy for T2DM treatment increases the risk of major CV events and deaths from HF, when compared to metformin.
Evangelos Oikonomou et al. · Current Pharmaceutical Design · 2023

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The claim is supported by comparative studies mentioned in the abstract.

Source

Novel Approaches to the Management of Diabetes Mellitus in Patients withCoronary Artery Disease

Evangelos Oikonomou et al. · Current Pharmaceutical Design · 2023

DOI 10.2174/1381612829666230703161058

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DOI resolved against Crossref · corpus check 2026-06-10

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