Research
Neural
Small-molecule GLP1RAs regulate both homeostatic and hedonic feeding through parallel neural circuits.
Practitioners can consider the dual impact of small-molecule GLP1RAs on different feeding behaviors.
StrongSupportsmedium confidence
This approach revealed that these compounds regulate both homeostatic and hedonic feeding through parallel neural circuits.
Why this rating
The study uses humanized GLP1R mouse models to investigate the effects.
Source
A Brain Reward Circuit Inhibited By Next-Generation Weight Loss Drugs
Elizabeth Godschall et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2024
otherCited 8×
Read the paper This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →