Research

Cellular

GIP(1-30)NH2 and GIP(1-42) have similar effects on human pancreatic islets.

Both GIP variants can be expected to have similar effects on insulin and glucagon secretion in pancreatic islets.

StrongSupportsmedium confidence
In vitro experiments on human islets showed similar insulinotropic and glucagonotropic effects of the two GIP variants.
Liva S. L. Krogh et al. · European Journal of Endocrinology · 2023

Why this rating

Based on the randomized controlled trial design involving healthy men.

Source

The naturally occurring GIP(1-30)NH2 is a GIP receptor agonist in humans

Liva S. L. Krogh et al. · European Journal of Endocrinology · 2023

DOI 10.1093/ejendo/lvac015

other · n=9Cited 8×
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DOI resolved against Crossref · corpus check 2026-06-10

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