Research
Cellular
Gastrointestinal side effects from tirzepatide are common but mild to moderate, with less than 5% treatment discontinuation.
Practitioners should be aware of potential mild gastrointestinal side effects when prescribing tirzepatide.
StrongSupportsmedium confidence
Gastrointestinal side effects (nausea, diarrhea, constipation) were common but mild to moderate, with <5% treatment discontinuation.
Why this rating
The claim is based on synthesized evidence from clinical studies.
Source
Efficacy and Safety of Tirzepatide for Weight Management in Non-Diabetic Obese Individuals: A Narrative Review
Mohammed Sallam et al. · Obesities · 2025
DOI 10.3390/obesities5020026
Meta-analysisCited 7×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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