Research
Cellular
Significant weight loss induced by GLP-1 receptor agonists (GLP-1Ra) may result in accelerated bone turnover and bone loss.
Healthcare providers should consider the impact of GLP-1Ra on bone health when prescribing these medications.
StrongSupportsmedium confidence
significant weight loss induced by GLP-1Ra may also result in accelerated bone turnover and bone loss.
Why this rating
The claim is based on observed outcomes related to GLP-1Ra.
Source
Effects of weight-loss interventions on bone health in people living with obesity
Julien Paccou et al. · Journal of Bone and Mineral Research · 2025
DOI 10.1093/jbmr/zjaf135
reviewCited 5×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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