Research
Cellular
Tissue concentrations and mRNA expression of GLP-1 and PYY do not differ between individuals with obesity and lean controls.
This indicates that obesity does not alter the local production of GLP-1 and PYY in the gut.
StrongRefutesmedium confidence
Neither were tissue concentrations and mRNA expression of both peptides different between both groups.
Why this rating
Based on the prospective single-center study design.
Source
Peptide YY and Glucagon-like Peptide-1 Secretion in Obesity
Jennifer Wilbrink et al. · Gastrointestinal Disorders · 2024
DOI 10.3390/gidisord7010003
cohort · n=24Cited 4×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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