Browse the evidence

Changes in muscle density over time might precede adverse outcomes such as falls and fractures.

Practitioners should monitor muscle density as a potential indicator of future health risks.

The degree of velum and tongue base obstruction was significantly associated with sleep apnea severity in positions 2, 3, and 4 after adjusting for age, BMI, tonsil size, and tongue position.

Understanding the specific obstructions can guide targeted treatments for sleep apnea.

Polymeric biomaterials can mimic gastric bypass by blocking excessive absorption.

Practitioners may explore less invasive methods for obesity treatment using polymeric biomaterials.

Understanding novel mutations in POMC and MC4R/MC3R may help identify strategies for the treatment and diagnosis of obesity, particularly childhood obesity.

This knowledge can guide interventions for childhood obesity.

Antidiabetic medications impact skeletal muscle lipid metabolism.

Practitioners should consider the effects of antidiabetic medications on lipid metabolism when treating patients.

Interventions like ASK-1 knockout, nitrate, and melatonin have increased thermogenesis and improved metabolic outcomes.

Consider these interventions to enhance thermogenesis in metabolic health strategies.

Metabolische unerwünschte Arzneimittelwirkungen (mUAW) von Psychopharmaka umfassen Gewichtszunahme, gestörte Glukosetoleranz, Diabetes mellitus und Dyslipidämie.

Healthcare providers should monitor metabolic parameters in patients on psychotropic medications.

Endoscopic sleeve gastroplasty (ESG) is associated with fewer complications and faster recovery compared to traditional bariatric surgery.

Clinicians can recommend ESG as a safer alternative for patients who are hesitant about traditional surgery.

Metabolische unerwünschte Arzneimittelwirkungen (mUAW) von Psychopharmaka umfassen Gewichtszunahme, gestörte Glukosetoleranz, Diabetes mellitus und Dyslipidämie.

Healthcare providers should monitor metabolic parameters in patients on psychotropic medications.

Lower body mass index is a significant independent factor for paraspinal muscle atrophy in preoperative lumbar spinal stenosis and lumbar disk herniation patients.

Practitioners should consider body mass index when assessing risk for muscle atrophy in these patients.

Reduced lumbar lordosis angle is a significant independent factor for paraspinal muscle atrophy in preoperative lumbar spinal stenosis and lumbar disk herniation patients.

Practitioners should consider lumbar lordosis angle when assessing risk for muscle atrophy in these patients.

Seven French raw-milk cheeses showed biological activities in vivo and in vitro.

Cheeses may be considered functional foods with potential health benefits.

Fractions (polar and apolar) reduced inflammatory markers in human chondrocytes.

Cheese fractions may have potential anti-inflammatory effects on joint health.

GLP-1-based therapies can lead to significant aesthetic issues in the face and neck, including midface volume loss and increased skin laxity.

Practitioners should be aware of these aesthetic concerns when treating patients on GLP-1 therapies.

Multimodal nonsurgical aesthetic treatments are recommended for addressing aesthetic issues in GLP-1 weight loss patients.

Practitioners should consider a combination of treatments for optimal aesthetic outcomes.

MitoQ supplementation reduced mitochondrial H2O2 emission capacity in skeletal muscle.

MitoQ may reduce oxidative stress in skeletal muscle for older adults.

Individuals with type 2 diabetes have significantly higher levels of inflammatory markers compared to an unaffected population.

Practitioners should consider monitoring inflammatory markers in patients with type 2 diabetes.

There is a significant positive association between C-reactive protein (CRP) levels and body mass index (BMI) in individuals with type 2 diabetes.

Monitoring BMI may provide insights into inflammation levels in diabetic patients.

The study reported no substantial differences in the numbers of adverse events between the two groups.

Both dietary approaches appear to be safe with respect to adverse events.

GLP‐1RAs triggered more gastrointestinal adverse events than placebo, with no in‐between difference.

Clinicians should be aware of the gastrointestinal side effects associated with GLP-1RAs when prescribing these medications.

There is a need for more research on the anabolic potential of non-animal-derived protein sources.

More research is needed to evaluate the effectiveness of non-animal protein sources for muscle health.

INV-202 was well tolerated with no serious or severe treatment-emergent adverse events.

INV-202 appears to be a safe option for individuals with metabolic syndrome.

Greater male variation in basal energy expenditure may be explained by greater male variation in the size of energy-demanding organs.

Understanding organ size variation may help tailor nutritional strategies for energy expenditure.

Metformin failed to prove beneficial effects in MASLD progression.

Avoid using metformin for treating MASLD progression as it has not shown benefits.