Browse the evidence

Age-related insulin resistance arises from interconnected mechanisms, including inflammaging, cellular senescence, and mitochondrial dysfunction.

Understanding these interconnected mechanisms can help in developing targeted interventions for older adults.

Muscle metabolic quality, rather than adiposity alone, emerges as a key determinant of insulin sensitivity in older adults.

Emphasizing muscle quality in interventions may improve insulin sensitivity in older patients.

Innovative obesity therapies could transform long-term outcomes of preeclampsia.

Practitioners should stay informed about new obesity therapies that may improve long-term health outcomes for women with preeclampsia.

Modern research has identified various factors that modulate insulin resistance, indicating the need for targeted therapies.

Identifying modulating factors can help in developing personalized treatment strategies for insulin resistance.

The visual-textual integrator of iFood achieved an accuracy of 51.38% in identifying diet images and information.

The accuracy of the app's data integration can be improved for better dietary insights.

Age was the only consistent demographic effect across time points.

Age should be considered when designing interventions for behavior change.

Data from supercentenarians can provide insights into the contributions of genetics, lifestyle choices, and epigenetics to longevity.

Research on supercentenarians can guide future studies on aging and longevity.

Fatty acids can reshape the bioavailability of eicosanoids and other lipid mediators.

Recognizing how fatty acids affect lipid mediators can inform dietary choices for managing inflammation.

Epicardial adipose tissue (EAT) may contribute to the pathophysiology observed in HFpEF.

Understanding the role of EAT may help in developing targeted therapies for HFpEF.

Stage 2 obesity requires excess waist circumference or waist-to-height ratio, along with symptoms or comorbid conditions.

Practitioners should assess waist measurements and related symptoms for obesity classification.

Autoantibody positive participants had higher HDL cholesterol and lower fasting C-peptide at baseline.

Higher HDL and lower fasting C-peptide may indicate different metabolic profiles in autoantibody positive individuals.

The evidence on the effect of vegetarian diet on the inflammatory and immunological biomarkers is poor.

Further research is needed to clarify the impact of vegetarian diets on inflammation and immunity.

Monosaccharides like glucose and fructose induce increases in intestinal de novo lipogenesis.

Emphasize the role of glucose and fructose in dietary planning for lipogenesis.

An understanding of postsurgical anatomy and management of bariatric surgical complications is essential for gastroenterologists.

Gastroenterologists need to be knowledgeable about bariatric surgery complications.

The incidence of obesity-related glomerulopathy has increased 10-fold in recent years.

Awareness of obesity-related kidney issues is essential for healthcare providers.

The intestinal microbiota may play a central role in the relationship between obesity and asthma.

Understanding microbiota's role may inform treatment strategies for asthma in obese patients.

The addition of 5% watermelon seed flour (WSF) to low-carbohydrate, high-protein bread enhances its volume compared to the control sample.

Incorporating 5% WSF can improve the volume of low-carb, high-protein bread.

Most upper airway anatomy was significantly associated with BMI among patients with OSA.

Practitioners should consider the impact of BMI on upper airway anatomy when assessing OSA.

All pharyngeal soft tissues were larger with greater BMI, including the volumes of the tongue, soft palate, and lateral walls.

Increased soft tissue volume with higher BMI should be considered in OSA management.

Female sex, older age, and lower BMI were associated with subsequent lower muscle density in older community-dwelling adults.

Practitioners should consider sex, age, and BMI when assessing muscle density in older adults.

Lower FMD was related to increased risk of previous fracture.

Monitoring FMD may help identify individuals at higher risk for fractures.

Changes in muscle density over time might precede adverse outcomes such as falls and fractures.

Practitioners should monitor muscle density as a potential indicator of future health risks.

The degree of velum and tongue base obstruction was significantly associated with sleep apnea severity in positions 2, 3, and 4 after adjusting for age, BMI, tonsil size, and tongue position.

Understanding the specific obstructions can guide targeted treatments for sleep apnea.

Sodium-glucose cotransporter 2 (SGLT2) inhibitors provide cardiovascular and renal protection in patients with type 2 diabetes mellitus (T2DM).

Practitioners should consider SGLT2 inhibitors as a treatment option for cardiovascular and renal protection in T2DM patients.