Browse the evidence

Current dietary practices reflect thousands of years of an almost Darwinian process of natural selection.

Understanding the historical context of dietary practices can inform current dietary recommendations.

More basic and applied research is needed to identify food consumption trends.

Increased research efforts can lead to better dietary policies and health outcomes.

Nitro-oleic acid treatment does not alter body weight in Nrf2fl/fl and ANKO mice on both high fat diet (HFD) and low-fat diet (LFD).

NO2-OA may not affect body weight, suggesting its effects are more focused on metabolic parameters rather than weight loss.

Obesity is defined as a body mass index of ≥30 kg/m² (≥27 kg/m² for those of Asian descent).

Practitioners should use these BMI thresholds for diagnosing obesity.

Section 1115 Demonstration Waivers are currently serving as a temporary funding mechanism for nutrition-related programs.

Understanding the temporary nature of current funding can inform program planning.

Approximately 83.0% of patients in both treatment groups receive TSH testing within a 1-year follow-up.

Practitioners should note that a high percentage of older adults on levothyroxine are monitored for TSH after initiating GLP-1 RAs.

TSH testing patterns did not differ between GLP-1 RAs and SGLT-2is.

Clinicians can expect similar TSH monitoring practices regardless of whether patients are on GLP-1 RAs or SGLT-2is.

The mean time to TSH testing was approximately 130.5 days for both groups.

Practitioners should be aware that TSH testing occurs on average about 130 days after treatment initiation.

PST receipt was not associated with concurrent and prospective increased self-care behaviors.

Practitioners may need to explore alternative interventions beyond PST to enhance self-care behaviors.

Future research should standardize economic evaluation methods in SET studies for better comparison across diverse interventions, settings, and populations.

Researchers should aim for consistent evaluation methods to enhance the validity of findings in SET studies.

No significant findings emerged in White women, African American men, or for the 8-10 week outcomes regarding WCadjBMI or WHRadjBMI.

Results may not be generalizable to all demographic groups, indicating the need for tailored approaches in interventions.

Urinary fructose and sugars intake were not significantly associated.

Practitioners should note that urinary fructose may not reliably indicate dietary fructose intake.

Only 7 studies (9%) had a sample size of more than 50 subjects.

Future studies should aim for larger sample sizes to improve the reliability of findings.

There was no significant effect of ADMP rank on interest in program participation (p = 0.34).

ADMP rank may not be a relevant factor in engaging this population for weight control programs.

A population study on urinary sodium excretion has not been done in Canada.

This indicates a gap in research that may affect public health policy.

Mean total costs per person-year decreased from $5227.25 to $4982.88 over three years.

Cost management strategies may be effective in obesity care over time.

Obesity has increased from 30.5% during 1999–2000 to 41.9% during 2017–2020.

Health practitioners should be aware of the rising obesity rates when designing interventions.

There is significant societal attention on the issues of overweight and obesity.

Practitioners should be aware of the societal context when addressing obesity in patients.

There was no significant difference in the cost of diabetes therapy between the two groups (p = 0.12).

Practitioners can consider that an open formulary may improve glycemic control without increasing costs.

An intensive lifestyle management program did not reduce clinical cardiovascular outcomes in patients with type 2 diabetes during 10 years of follow-up.

Practitioners should note that intensive lifestyle interventions may not significantly impact cardiovascular outcomes in this population.

More studies are needed to provide conclusive results on the efficacy of eHealth interventions.

Continued research is essential for validating the effectiveness of eHealth interventions.

More studies are needed to provide conclusive results on the efficacy of eHealth interventions.

Future research is essential to validate the effectiveness of eHealth interventions.

Few diabetes prevention program (DPP) studies investigate why these interventions work.

Practitioners should be aware that the mechanisms behind DPP effectiveness are not well understood.

There is no compelling evidence to support any specific mechanism, mediator, or moderator (MMM) in DPPs.

Practitioners should consider that current evidence does not support specific mechanisms in DPPs.