Browse the evidence

The European Society of Cardiology guidelines provide up-to-date recommendations for managing diabetes and cardiovascular disease.

Practitioners should refer to these guidelines for current management strategies.

The tailored nutrition intervention resulted in higher total daily energy and protein intake levels.

Implementing tailored nutrition protocols can significantly enhance energy and protein intake in recovery.

Evidence from other studies supports the efficacy of remote interventions for weight loss among cancer survivors.

Remote interventions may still be a viable option for weight loss in cancer survivor populations.

Meer dan 80 % van de hart- en vaatziekten is direct gerelateerd aan leefstijl.

Leefstijlveranderingen zijn essentieel voor het voorkomen van hart- en vaatziekten.

Gezonde leefgewoonten zijn de beste manier om de cardiovasculaire gezondheid te behouden of te bevorderen.

Professionals moeten gezonde leefstijladviezen geven om cardiovasculaire gezondheid te verbeteren.

The paper aims to provide practical recommendations for return to sport after ACL reconstruction.

Practitioners can look forward to evidence-based guidelines for aiding athletes in their recovery.

Fewer participants in the on-paper group reported to have experienced significant weight loss in their adult life (70.0% vs 100%, p = 0.001).

Practitioners may consider that individuals who prefer paper surveys may have less successful weight loss experiences.

The digital group reported significantly greater weight loss maintenance (86.5% vs 43.8% of the initial weight loss, p = 0.008).

Practitioners may find that digital engagement leads to better weight loss maintenance.

Functional training is defined as a physical interventional approach that enhances human performance according to individual goals.

This definition can guide practitioners in designing functional training programs.

Carbohydrate intake of 30-90 g/hour during exercise fuels prolonged activity and delays fatigue by maintaining blood glucose and muscle glycogen levels.

For rides longer than an hour, consume 30-90g of carbohydrates per hour. Use a mix of glucose and fructose for better absorption. Practice your nutrition strategy in training to avoid stomach issues.

Creatine supplementation significantly improves anaerobic power (Wingate peak and mean power) regardless of whether the individual is performing resistance training or non-resistance training.

Take creatine daily to boost your high-intensity performance (like sprinting or sports). You do not need to be in a gym or doing weights to get these power benefits.

Metabolic (bariatric) surgery is indicated for Type 2 Diabetes patients with BMI > 30 kg/m2 and can lead to significant diabetes remission.

If you have Type 2 Diabetes and a BMI over 30, metabolic surgery is a medically indicated option that can lead to diabetes remission in 45-95% of cases. It requires lifelong monitoring but offers superior outcomes compared to medication alone.

First-line therapy for obesity involves lifestyle modification (energy-restricted diet and increased physical activity) aiming for 5-15% weight loss over 6 months, supported by pharmacotherapy or bariatric surgery for higher BMI or comorbidities.

Start with a 600 kcal daily deficit and 30-60 minutes of moderate exercise most days. Aim for 5-15% weight loss over 6 months. If BMI is >30 (or >27 with comorbidities), discuss pharmacotherapy (e.g., GLP-1 agonists) or bariatric surgery (if BMI >=40 or >=35 with comorbidities) with your doctor.

Meal replacement interventions improve cardiometabolic health outcomes, including glycemic control, blood pressure, lipids, and liver fat, often independent of or proportional to the degree of weight loss.

Using meal replacements to lose weight not only helps you shed pounds but also significantly improves your blood sugar, blood pressure, and liver health. This is especially true if you have Type 2 Diabetes, where significant weight loss can lead to remission.

Sustained weight loss of 5-10% or greater through negative energy balance interventions (behavioral, pharmacological, or surgical) prevents, reduces, or resolves obesity-related complications such as type 2 diabetes, hypertension, and fatty liver disease.

To significantly lower your risk of type 2 diabetes and other obesity-related diseases, you need to achieve and maintain a weight loss of at least 5-10% of your body weight. This can be done through lifestyle changes, medications, or surgery. The key is that the weight loss must be sustained over the long term, not just short-term dieting.

Greater magnitude of weight loss (e.g., >10-15%) is required to achieve remission of type 2 diabetes, whereas moderate weight loss (5-10%) is sufficient for prevention or delay.

If you want to prevent type 2 diabetes, losing 5-10% of your body weight is a great start. However, if you already have type 2 diabetes and want to achieve remission, you likely need to lose more than 10-15% of your body weight and keep it off.

An intensive lifestyle intervention (ILS) focused on weight loss and increased physical activity reduces the incidence of type 2 diabetes by 58% compared to placebo in high-risk adults with prediabetes, with effects sustained over 21 years.

To significantly lower your risk of developing type 2 diabetes, focus on losing 7% of your body weight and getting at least 150 minutes of moderate physical activity per week. This lifestyle approach is proven to be more effective than medication (metformin) for preventing diabetes in high-risk individuals, with benefits lasting for decades.

Dietary patterns significantly shape the gut microbiome, with fiber-rich diets increasing diversity and beneficial bacteria, while high-fat diets decrease diversity and promote pro-inflammatory species.

Prioritize fiber-rich foods (vegetables, fruits, whole grains) to support microbial diversity and beneficial bacteria. Limit high-fat, processed foods which reduce diversity and promote inflammation.

Significant weight loss (typically >10%) induced by intensive lifestyle interventions (very low-calorie diets) or metabolic bariatric surgery can induce remission of type 2 diabetes (HbA1c < 6.5% without medication), primarily by reversing ectopic fat accumulation in the pancreas and liver.

If you have recently been diagnosed with Type 2 diabetes, prioritize significant weight loss immediately. Clinical trials show that losing a substantial amount of weight (often via structured, low-calorie diet programs) can put your blood sugar into remission (normal levels without medication), especially if you act within the first few years of diagnosis. This reverses the fat accumulation in your pancreas and liver that is driving the disease.

Intensive lifestyle intervention (≥150 min/week moderate exercise and 500-1000 kcal/day caloric deficit) significantly reduces the incidence of new-onset type 2 diabetes compared to placebo, with benefits persisting for at least 21 years.

To prevent type 2 diabetes, aim for 150 minutes of moderate exercise per week and eat 500-1000 calories less than you burn daily. This combination helps you lose 7% of your body weight. The benefits last for decades, reducing your risk of diabetes and related complications like heart disease and kidney issues. Start with small, sustainable changes to diet and activity.

Carbohydrate-restricted diets lead to significant reductions in body weight, body fat percentage, and visceral adipose tissue compared to higher-carbohydrate diets.

Cutting carbs to under 45% of your calories is an effective strategy for losing body fat and visceral fat. You will likely lose some weight and body fat percentage, especially if you are overweight. Be aware that you might lose some lean muscle mass along with the fat, so monitoring your strength and considering resistance training is advisable.

Bariatric surgery (Roux-en-Y gastric bypass and sleeve gastrectomy) is recommended for individuals with BMI > 35 kg/m² regardless of comorbidities, and for those with BMI 30-34.9 kg/m² and metabolic diseases.

Bariatric surgery is now recommended for individuals with a BMI over 35, even without other health issues, and for those with a BMI of 30-34.9 who have metabolic diseases. Procedures like Roux-en-Y gastric bypass and sleeve gastrectomy provide substantial long-term weight loss and improve quality of life.

Every 5 kg of weight loss from anti-obesity treatment reduces the risk of myocardial infarction, stroke, and heart failure.

Losing just 5 kg (about 11 lbs) through anti-obesity treatments can significantly lower your risk of heart attack, stroke, and heart failure. This highlights the importance of achieving even modest weight loss for long-term cardiovascular health. Work with your healthcare provider to find a safe and effective weight management strategy.

Weight loss of 7-10% is required to resolve steatohepatitis (MASH) and regress fibrosis, whereas 5% loss primarily improves steatosis.

To reverse liver inflammation, aim for a 7-10% total body weight loss through diet and exercise. Losing 5% helps reduce liver fat, but hitting the higher threshold is necessary to fix the actual liver damage (inflammation). Combine caloric restriction with both aerobic and resistance training to preserve muscle mass.