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Body fat percentage was inversely associated with the energy cost of weight (r = -0.38) and fat mass (r = -0.40) gains.

Higher body fat percentage may indicate lower energy efficiency in gaining weight.

Semaglutide users experienced modest weight reductions ranging from 0.42 kg to 1.16 kg.

Practitioners may consider Semaglutide for modest weight loss in type 2 diabetes management.

The study identified key themes for safe practices in BMT, including psychological health, sleep apnea, cardiovascular disease, liver health, and dietetic assessment.

Practitioners should consider these health factors when evaluating patients for BMT.

Prevention of overweight and obesity is crucial and should be addressed socially.

Efforts to prevent obesity should involve community and societal strategies.

Lacto-ovo-vegetarians had lower protein consumption than non-vegetarians throughout the study but still achieved adequate protein intake.

Adequate protein intake can be achieved even with lower consumption in vegetarians.

Innovative solutions are needed to implement sustainable lifestyle modification interventions for T2D.

Practitioners should advocate for and develop innovative strategies to enhance lifestyle intervention adherence.

Obesity increases the risk of postoperative complications following elective surgery.

Surgeons should consider obesity as a significant risk factor when planning surgeries.

An interdisciplinary approach is necessary for effective weight loss treatment in obese patients before joint replacement surgery.

Healthcare teams should collaborate across disciplines to optimize weight loss strategies for these patients.

The online exercise program had good feasibility and adherence, with 97% attendance and 98% participant satisfaction.

Practitioners can consider online exercise programs as a feasible option for engaging older adults.

People with physical disabilities (PWD) report more sedentary time compared to people without disabilities (PWoD) (β = 0.34; 95 % CI = 0.16-0.52, p < 0.001).

Practitioners should be aware that PWD may require tailored interventions to reduce sedentary behavior.

PWD have greater odds of reporting zero total physical activity compared to PWoD (OR = 5.18, 95 % CI = 2.19-12.24, p < 0.001).

Interventions for PWD should focus on increasing overall physical activity levels.

The Brain and Body Health (BB-Health) study aims to demonstrate the feasibility of a multicomponent nutritional supplement (MCNS) and weight loss (WL) intervention for older adults with obesity.

Practitioners may consider the potential of MCNS and WL interventions for older adults with obesity.

Overfeeding led to an average body weight gain of 7.3 ± 0.4 kg.

Practitioners should be aware that overfeeding can lead to significant weight gain.

Adipocyte browning enhances energy expenditure, improves insulin sensitivity, and mitigates lipid accumulation.

Adipocyte browning could be targeted in therapies for obesity and metabolic diseases.

Bariatric surgery is associated with a 42.4% reduction in fat mass (FM) at 6 months, 49.7% at 12 months, and 49.7% at 24 months.

Bariatric surgery significantly reduces fat mass in patients over a 24-month period.

Both bariatric surgery and GLP-1RA treatment improve the fat-free mass (FFM) to fat mass (FM) ratio.

Both interventions are effective in improving body composition ratios.

No significant adverse events were recorded during the study.

The combination appears to be safe for use in the studied population.

Traditional interventions related to diet and exercise have fallen short in addressing obesity.

New treatment approaches may be necessary to effectively manage obesity.

Patients show a strong commitment to obtaining and maintaining weight-loss medication despite disruptions to their daily lives.

Health care providers should recognize the dedication of patients in managing their weight-loss treatment.

Health care professionals align patients' expectations for immediate weight loss while navigating moral reasoning about weight loss methods.

Practitioners should be aware of the expectations patients have and the ethical considerations in weight-loss discussions.

Bariatric medicine includes a range of medical and surgical interventions to address obesity.

Practitioners should consider a variety of interventions when managing obesity.

Among 1,059,605 Veterans with incident prediabetes, 12,009 (1.1%) were prescribed metformin during an average 3.4 years of observation after diagnosis.

Practitioners should note that metformin is prescribed to a small percentage of Veterans with prediabetes.

Over 20% of Veterans with prediabetes attended a comprehensive structured lifestyle modification clinic or program.

Practitioners should encourage participation in lifestyle modification programs for Veterans with prediabetes.

Recommendations for collaborative action include developing obesity education and care standards that incorporate patients' perspectives.

Healthcare systems should prioritize patient-centered approaches in obesity care.