Browse the evidence

Endoscopic sleeve gastroplasty (ESG) is more cost-effective than semaglutide over a 5-year time horizon, with an incremental cost-effectiveness ratio (ICER) of -$595,532/QALY.

Practitioners may consider ESG as a more cost-effective option for treating class II obesity compared to semaglutide.

In men, resistance exercise has a similar effect on 24-h energy expenditure (EE) as a comparable bout of aerobic exercise.

Both resistance and aerobic exercises can be used interchangeably for managing energy expenditure.

Liraglutide has additional benefits in reducing cardiovascular events in patients with type 2 diabetes mellitus.

Liraglutide may be beneficial for patients with T2DM beyond weight loss.

Both groups experienced a decrease in per member per month (PMPM) expenses, with a 38% decrease in the experimental group.

Group interventions may also be cost-effective for CAD patients.

There were few deviations from the prescribed diet among participants.

Maintaining a structured dietary plan can minimize deviations and support adherence.

The associations between assigned energy level and actual intake were high for all groups.

Understanding the strong correlation between assigned and actual energy intake can help in designing effective dietary interventions.

Over 10 years, the MTM intervention is anticipated to potentially be associated with 18,257,000 averted hospitalizations and reductions in health care expenditures of $484.5 billion.

Long-term implementation of MTMs could significantly reduce hospitalizations and healthcare costs.

Forty-one percent of ILI participants who achieved ≥175 min·wk at year 1 maintained this threshold of PA at year 4.

Maintaining high levels of physical activity is achievable for some individuals following intensive lifestyle interventions.

Only a small fraction of the population with obesity are optimally treated.

There is a need for improved strategies to treat obesity effectively.

Fish was the largest dietary contributor to n-3 fatty acid intake among the top 15% of consumers.

Encouraging fish consumption can significantly enhance n-3 fatty acid intake among those who are already consuming higher amounts.

Multifrequency bioelectrical impedance analysis (MF-BIA) is an acceptable alternative for tracking changes in fat mass (FM) and fat-free mass (FFM) during a combined diet and exercise program in young, athletic men.

Practitioners can use MF-BIA for monitoring body composition changes in similar populations.

Caloric restriction is associated with increased dietary restraint and negative energy balance.

Caloric restriction can enhance dietary control and promote weight loss through negative energy balance.

Voluntary energy intake following dietary restriction increased above the initial amount required for body weight maintenance.

Practitioners should expect increased voluntary intake after periods of dietary restriction.

The study of exercise as a preventative or therapeutic treatment is increasingly interdisciplinary and impactful.

Researchers and practitioners should collaborate across disciplines to enhance exercise interventions.

Vegan diets can be health-promoting and may offer certain important advantages compared to typical Western eating patterns.

Health professionals should recognize the potential health benefits of vegan diets.

A precise and practical vegan nutrition guide for health professionals is lacking.

There is an urgent need for health professionals to have access to a vegan nutrition guide.

Exercise attenuated the energy imbalance by 50%, reducing appetite and increasing energy requirements.

Incorporating regular exercise can significantly help manage appetite and energy balance during weight regain.

There is no single mode of physical activity that is superior for weight loss or prevention of weight gain.

Advise clients that various forms of physical activity can be effective for weight management, and they should choose what they enjoy.

Caffeine could not fully restore power output to levels seen with normal glycogen availability.

Caffeine may enhance performance but should not be relied upon to completely counteract the effects of low glycogen.

Increasing energy demand through physical activity may alleviate some of the adverse metabolic changes that are associated with aging.

Encouraging physical activity in elderly patients may improve their metabolic health.

Current evidence suggests a potential role for low-GI carbohydrates in weight-reducing regimens.

Low-GI carbohydrates could be integrated into weight loss programs.

A comprehensive weight loss program can reduce weight by 6% to 7% but confers no clinically significant effects compared with standard care.

Practitioners should note that while weight loss programs can lead to some weight reduction, they may not result in significant clinical improvements.

The trajectory of percent weight change during caloric restriction can be modeled using simple nonlinear functions based on age, total daily energy expenditure, percent caloric restriction, and sex.

Counselors can tailor weight loss expectations based on individual characteristics.

Calories are the source of health problems affecting billions of people.

Understanding the impact of calorie intake is crucial for addressing health issues.