Browse the evidence

Insulin users incur at least double the one-year T2D-HE compared to non-users within each BMI category.

Insulin therapy significantly increases healthcare costs for patients with type 2 diabetes.

Metabolic health, rather than obesity, is a key predictor of adverse events in chronic coronary syndrome (CCS) prevention.

Practitioners should prioritize assessing metabolic health over BMI in cardiovascular risk evaluations.

Approximately 80% of subjects had cholesterol levels outside recommended values after 6 years.

Monitoring cholesterol levels is important for older adults, even after exercise interventions.

LCD may provide better glycemic control and is favorable for weight control and atherosclerosis prevention.

Adopting a low-carb diet could be beneficial for managing diabetes and preventing related health issues.

MetFlex to fat displayed satisfactory test-retest reliability (intraclass correlation coefficient > 0.70) for several outcomes.

This method can reliably assess metabolic flexibility to high-fat meals in healthy individuals.

Overnight changes in substrate oxidation following a high-fat dinner meal represent a unique aspect of MetFlex.

Practitioners should consider overnight metabolic responses when assessing dietary impacts.

Postprandial plasma lipids and lipoproteins were examined after a 2-week low-carbohydrate diet compared to a 2-week low-fat diet.

This study provides insights into how different dietary approaches may affect lipid and lipoprotein levels post-meal.

SGLT2 inhibitors are associated with reductions in blood pressure and body weight, in addition to decreasing hyperglycemia.

Practitioners can consider SGLT2 inhibitors as a treatment option for managing blood pressure and weight in T2DM patients.

Die Gewichtsentwicklung in den ersten Wochen bis Monaten nach Initialisierung einer Therapie ist der stärkste Prädiktor für Gewichtszunahme assoziiert mit AP und AD.

Monitoring weight in the early stages of treatment can help predict long-term weight gain.

The WIG score shows moderate accuracy in predicting anti-DM dose reductions at baseline and after 3 months of weight loss efforts.

The WIG score can be used by healthcare providers to identify patients likely to reduce diabetes medication with weight loss.

Resistant starch has potential health benefits including improving glycemic control, increasing satiety, and gut health.

Incorporating resistant starch into diets may enhance glycemic control and satiety.

The effectiveness of ESG is influenced by the patient's body mass index (BMI), being more effective in those with lower BMIs.

Practitioners should assess BMI when recommending ESG to optimize treatment outcomes.

Sleeve gastrectomy can result in weight loss up to 23% at 1 year and is associated with a lower risk of malabsorption compared to Roux-en-Y gastric bypass.

Surgeons and healthcare providers should consider sleeve gastrectomy as a viable option for weight loss in transplant candidates.

Die Gewichtsentwicklung in den ersten Wochen bis Monaten nach Initialisierung einer Therapie ist der stärkste Prädiktor für Gewichtszunahme assoziiert mit AP und AD.

Monitoring weight in the early stages of treatment can help predict long-term outcomes.

The Open Formulary group had a modest weight reduction of −2.5 kg ± 4.4 kg.

Practitioners may note that an open formulary can also contribute to modest weight loss in patients.

Obesity predicts cardiovascular disease mortality.

Practitioners should consider obesity as a significant risk factor for cardiovascular disease mortality.

Higher BMIs are associated with the development of chronic kidney disease.

Weight management may be crucial for preventing chronic kidney disease.

The removal of amino acids during hemodialysis contributes substantially to protein malnutrition in patients.

Practitioners should ensure adequate protein intake for patients undergoing hemodialysis.

Participants with high baseline HbA1c experienced the greatest improvements in physical health (3.84 points) and mental health (3.3 points) scores.

High-risk individuals may see substantial improvements in both physical and mental health through digital health coaching.

Higher total fat intake was associated with lower total mortality (HR 0.77).

Increasing total fat intake may contribute to improved longevity.

HRmax and RER were significantly higher during the PSP test compared to the PIP test.

The PSP protocol may elicit a greater cardiovascular and metabolic response than the PIP protocol.

Only 50% of subjects demonstrated the plateau phenomenon in oxygen uptake with either protocol.

Practitioners should be aware that not all athletes will reach the plateau during VO2max testing, which may affect test interpretation.

Lower HbA1c is associated with 0.17 to 0.22 standard deviation better cognitive function across all domains.

Improving diabetes control to achieve lower HbA1c levels may enhance cognitive function in individuals with type 2 diabetes.

There were no significant differences in changes in waist circumference, BMI, body fat, or metabolic risk factors between the two groups.

Practitioners may consider that time-restricted eating does not provide additional metabolic benefits compared to daily calorie restriction.