Browse the evidence

Psychosocially vulnerable young adults can achieve better mental well-being and fewer problems.

Practitioners should focus on mental well-being interventions for vulnerable young adults.

Generalized and visceral adiposity were associated with reduced cognitive scores, after adjustment for cardiovascular risk factors, educational level, and vascular brain injury.

Strategies to prevent or reduce adiposity may help preserve cognitive function.

The combination of verbal instructions and mirror self-motor observation attenuated the decrease in torque output during isokinetic contractions.

Combining verbal cues with mirror observation may enhance performance in resistance training.

The verbal + MO-mirror condition resulted in lower antagonist/agonist coactivation.

Lower coactivation may improve efficiency in resistance exercises.

The combination of both cueing modalities elicits a more effective contraction strategy during knee-extension exercise.

Using both internal focus and mirror observation can enhance training effectiveness.

Understanding factors associated with paraspinal muscle atrophy can help develop personalized rehabilitation protocols for postoperative recovery.

Practitioners can use these findings to tailor rehabilitation strategies for better recovery outcomes.

In patients with cardiovascular disease and diabetes mellitus, lower-extremity muscle strength is significantly associated with peak oxygen uptake (VO 2peak).

Practitioners should focus on improving lower-extremity muscle strength in patients with CVD and DM to enhance exercise capacity.

The interaction between diabetes mellitus and lower-extremity muscle strength significantly affects exercise capacity.

Understanding the interaction between diabetes and muscle strength can help tailor exercise programs for better outcomes.

Continuous glucose monitoring (CGM) may be a useful tool for promoting dietary awareness and self-management among non-diabetic athletes.

Practitioners may consider using CGM to enhance dietary management in trained athletes.

Daily yoga was significantly associated with changes in perceived athletic performance across the menstrual cycle.

Implementing daily yoga may enhance perceived athletic performance in women during their menstrual cycle.

Regular follow-up is crucial for tracking outcomes and evaluating evolving aesthetic needs in GLP-1 weight loss patients.

Practitioners should implement regular follow-ups to ensure effective treatment and satisfaction.

High cardiorespiratory fitness is associated with 0.08 to 0.13 standard deviation better global cognitive function, executive function, and attention.

Encouraging higher cardiorespiratory fitness may improve cognitive health in individuals with type 2 diabetes.

Serum levels of brain-derived neurotrophic factor (BDNF) significantly increased in the TRF group.

Increased BDNF levels may indicate improved brain function related to eating behaviors in women undergoing TRF.

Cognitive restriction scores were higher in the TRF group compared to the control group.

Higher cognitive restriction scores in the TRF group suggest improved self-regulation in eating behaviors.

The exercise goal of 10,000 steps/day was unachievable for the participants.

Practitioners should consider setting realistic exercise goals for pregnant women to enhance adherence.

GIPR agonism may reduce gastrointestinal adverse effects associated with GLP-1R agonism.

GIPR agonists may help mitigate gastrointestinal side effects for patients using GLP-1R agonists.

Concurrent exposure to liraglutide and a GIPRA is hypothesized to produce fewer GI adverse effects than exposure to liraglutide alone.

This suggests a potential strategy for reducing side effects in patients using liraglutide.

There has been a revolution in understanding the molecular and neural control of appetite and body weight.

Understanding these mechanisms can inform treatment strategies for obesity.

GLP-1RA users had a lower risk of dementia (HR, 0.63; 95% CI, 0.50-0.81) compared to other antidiabetic drug users.

Practitioners may consider GLP-1RAs as a treatment option for reducing dementia risk in this population.

Intranasal delivery of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) could overcome the limitations of subcutaneous administration for obesity treatment.

Practitioners should consider intranasal delivery methods for improving patient adherence and reducing side effects.

Chronic co-administration of OXT and GLP-1 decreases body weight without changing food intake.

Combining OXT with GLP-1 may be an effective strategy for reducing body weight in obese populations.

Single injection of OXT/GLP-1 additively decreases food intake.

Using OXT in conjunction with GLP-1 may enhance appetite suppression effects.

Allodynia was observed in 4 patients associated with dose escalation of semaglutide.

Clinicians should be aware of the potential for allodynia in patients taking semaglutide.

BI 1820237 treatment was associated with transient nausea and vomiting at higher doses.

Practitioners should monitor for gastrointestinal side effects when prescribing BI 1820237.