Browse the evidence

Atherogenicity (ATI) is directly correlated with serum cholesterol (R = +0.73).

Practitioners should monitor serum cholesterol levels in relation to dietary fatty acid intake.

Atherogenicity (ATI) and Thrombogenicity (THI) indices are strongly associated with long-term coronary heart disease (CHD) mortality.

Practitioners should consider the impact of dietary fatty acids on long-term CHD risk.

The proposed wireless acquisition system for grip force monitoring demonstrates excellent performance in real-time signal acquisition and grip force prediction.

Practitioners can utilize this system for effective muscle monitoring in various applications.

The grip force prediction model established using dual-channel sEMG signals achieved an R2 of 0.9215.

This high R2 value indicates reliable grip force predictions, useful for training and rehabilitation.

The system is characterized as portable, wearable, low-cost, and easy to operate.

The system's design makes it accessible for various users in fitness and rehabilitation settings.

Probability of mild cognitive impairment (MCI) or probable dementia (PD) differed by type 2 diabetes (T2D) subgroup.

Healthcare providers should consider T2D subgroup characteristics when assessing cognitive health risks.

The highest probability of MCI/PD was found in the T2D subgroup characterized by severe obesity.

Focus on weight management strategies in T2D patients to mitigate cognitive decline risks.

There is a lack of a gold-standard method for returning to sport after an ACL injury.

Practitioners should be aware that there is no universally accepted protocol for returning athletes to sport after ACL injuries.

There is controversy regarding the variables involved in ACL injuries.

Practitioners should consider the complexity and variability in ACL injuries when developing recovery plans.

The term 'ultra-processed food' emerged in the 1980s and refers to highly-processed convenience foods that are often energy-dense and poor in nutrients.

Practitioners should recognize the historical context and definition of ultra-processed foods when discussing nutrition.

53.5% of participants are at risk of exercise addiction and 46.5% are addicted to exercise.

Practitioners should be aware that a significant portion of regular exercisers may be at risk or addicted to exercise.

GLP-1-based therapies can lead to significant aesthetic issues in the face and neck, including midface volume loss and increased skin laxity.

Practitioners should be aware of these aesthetic concerns when treating patients on GLP-1 therapies.

Multimodal nonsurgical aesthetic treatments are recommended for addressing aesthetic issues in GLP-1 weight loss patients.

Practitioners should consider a combination of treatments for optimal aesthetic outcomes.

MitoQ supplementation reduced mitochondrial H2O2 emission capacity in skeletal muscle.

MitoQ may reduce oxidative stress in skeletal muscle for older adults.

Individuals with type 2 diabetes have significantly higher levels of inflammatory markers compared to an unaffected population.

Practitioners should consider monitoring inflammatory markers in patients with type 2 diabetes.

There is a significant positive association between C-reactive protein (CRP) levels and body mass index (BMI) in individuals with type 2 diabetes.

Monitoring BMI may provide insights into inflammation levels in diabetic patients.

The paper developed the first consensual definition of functional training using an international e-Delphi method.

Practitioners can refer to this consensual definition for clarity in functional training.

A proposal was made to avoid the distinction between functional training and the general concept of training.

Practitioners should consider this proposal when defining and applying functional training.

The incidence of peripheral neuropathy (PN) differs by type 2 diabetes (T2D) subgroup.

Healthcare providers should consider T2D subgroups when assessing PN risk.

Long-term metformin (850 mg twice daily) and intensive lifestyle interventions do not reduce major cardiovascular events in individuals with prediabetes, despite significantly delaying or preventing the onset of type 2 diabetes.

Taking metformin or following a strict lifestyle program to prevent diabetes does not guarantee protection against heart attacks or strokes, even if you successfully avoid developing diabetes. In this long-term study, these interventions prevented diabetes but did not lower cardiovascular event rates compared to placebo, likely because other risk factors (blood pressure, cholesterol) were managed by standard care. Focus on comprehensive risk management, not just glucose control.

Statin therapy causes a moderate, dose-dependent increase in the diagnosis of new-onset diabetes and worsening glycaemia, with high-intensity regimens producing a 36% relative increase compared to a 10% increase for low/moderate-intensity regimens.

If you are taking statins, be aware that they can slightly raise your blood sugar, especially at higher doses. This increases your risk of being diagnosed with diabetes, particularly if your blood sugar was already near the threshold. However, the heart protection benefits of statins far outweigh this small risk. Regular monitoring of your blood sugar is recommended.

The absolute excess risk of new-onset diabetes from statins is highest in individuals whose baseline glycaemic markers are already close to the diagnostic threshold for diabetes.

If you have pre-diabetes or high-normal blood sugar, your risk of developing diabetes while on statins is higher than someone with normal blood sugar. This does not mean you should stop the statin, but it does mean you should monitor your blood sugar more closely and focus on lifestyle changes to keep your blood sugar in check.

Visceral feedback from the gut activates GCG neurons in the cNTS to promote long-lasting satiety (tens of minutes) that tracks cumulative food intake.

The physical presence of food in your stomach and intestines activates GCG neurons, which promote a feeling of fullness that lasts for tens of minutes. This visceral feedback tracks how much you have eaten, contributing to long-lasting satiety after a meal.

Rare deleterious variants in six specific effector genes (MC4R, PCSK1, POMC, CALCR, BSN, and CORO1A) are significantly associated with BMI at the population level, with CORO1A being a newly identified genetic risk factor for obesity.

Genetic testing can identify individuals with rare variants in genes like CORO1A, MC4R, or PCSK1 who are at higher risk for severe obesity. Knowing this early can guide personalized prevention strategies, such as early lifestyle interventions or targeted pharmacological therapies, before significant weight gain occurs.