Browse the evidence

Chronic treatment of obese insulin-resistant wild-type animals with a long-acting GIPR agonist prevented rosiglitazone-induced weight gain and hyperphagia.

GIPR agonists may be beneficial in managing weight gain and overeating in insulin-resistant conditions.

GIPR agonism enhances the insulin-sensitizing effect of the thiazolidinedione rosiglitazone.

Incorporating GIPR agonists could enhance the effectiveness of insulin-sensitizing medications.

The evolution of health information technologies has been documented through case studies, including type 2 diabetes.

Case studies can be used to illustrate the effectiveness of new health technologies.

Yoga significantly improved the expression of OGG1 protein, indicating enhanced DNA repair in T2D subjects (17.55; P = .034).

Yoga may enhance DNA repair mechanisms in individuals with type 2 diabetes.

The beneficial effect of yoga on DNA damage in T2D subjects is mediated by the mitigation of oxidative DNA damage and enhancement of DNA repair.

Yoga's benefits for DNA damage in type 2 diabetes are linked to its effects on oxidative stress and DNA repair.

An understanding of postsurgical anatomy and management of bariatric surgical complications is essential for gastroenterologists.

Gastroenterologists need to be knowledgeable about bariatric surgery complications.

Acute low-intensity resistance exercise with blood flow restriction (LIRE-BFR) may induce increases in central blood pressure and pulse wave velocity in healthy young people.

Practitioners should be aware that LIRE-BFR can lead to increased central blood pressure and arterial stiffness in young clients.

Anaerobic exercise decreases systemic pH and increases metabolic acidosis in athletes.

Athletes should be aware that anaerobic exercise can lead to increased metabolic acidosis.

Dietary patterns intersect with psychosocial vulnerabilities linked to risks of antisocial behavior.

Understanding dietary influences can help address psychosocial issues related to antisocial behavior.

Obesity is a modern epidemic with substantial health and economic impact.

Recognize obesity as a critical public health issue requiring attention.

The incidence of obesity-related glomerulopathy has increased 10-fold in recent years.

Awareness of obesity-related kidney issues is essential for healthcare providers.

The intestinal microbiota may play a central role in the relationship between obesity and asthma.

Understanding microbiota's role may inform treatment strategies for asthma in obese patients.

There was no significant change in diastolic blood pressure after 8 weeks of resistance training in both groups.

Practitioners should note that while systolic BP decreases, diastolic BP may not be affected by resistance training in this population.

Utilization of anti-obesity agents is rising in reproductive-age females planning for future pregnancy.

Practitioners should be aware of the increasing use of anti-obesity agents in this population.

The definitive role of assisting weight loss with medication prior to pregnancy remains to be established.

Further research is needed to clarify the role of anti-obesity medications in weight loss for women prior to pregnancy.

Central blood pressure (BP) correlates more with future cardiovascular risk than peripheral BP.

Practitioners should consider central BP measurements for assessing cardiovascular risk in obese patients.

There is no definitive evidence of causality between ultra-processed foods and adverse health outcomes.

Practitioners should be cautious in making definitive claims about UPFs and health outcomes.

The authors propose a paradigm for guiding the formulation of UPFs and their selection by consumers.

Food designers and consumers should consider this paradigm to improve UPF choices.

The addition of 5% watermelon seed flour (WSF) to low-carbohydrate, high-protein bread enhances its volume compared to the control sample.

Incorporating 5% WSF can improve the volume of low-carb, high-protein bread.

The amino acid profile of bread with 5% WSF is higher than that of the control bread.

Using WSF can enhance the amino acid content of bread, beneficial for nutrition.

Most upper airway anatomy was significantly associated with BMI among patients with OSA.

Practitioners should consider the impact of BMI on upper airway anatomy when assessing OSA.

All pharyngeal soft tissues were larger with greater BMI, including the volumes of the tongue, soft palate, and lateral walls.

Increased soft tissue volume with higher BMI should be considered in OSA management.

Female sex, older age, and lower BMI were associated with subsequent lower muscle density in older community-dwelling adults.

Practitioners should consider sex, age, and BMI when assessing muscle density in older adults.

Lower FMD was related to increased risk of previous fracture.

Monitoring FMD may help identify individuals at higher risk for fractures.