Browse the evidence

Non-dieting approaches to treating obesity include medications, gastrointestinal devices, and bariatric surgery.

Practitioners should consider these non-dieting treatment options for obesity management.

Adipose tissue browning is linked to improved metabolic and cardiovascular health.

Promoting adipose tissue browning may enhance metabolic and cardiovascular health.

Interventions like ASK-1 knockout, nitrate, and melatonin have increased thermogenesis and improved metabolic outcomes.

Consider these interventions to enhance thermogenesis in metabolic health strategies.

White adipose tissue browning mitigates inflammation and improves cardiometabolic health.

Encouraging white adipose tissue browning may reduce inflammation and enhance cardiometabolic health.

Obesity prevalence is projected to grow by 40% in the next decade.

Health professionals should prepare for increased obesity-related health issues.

The incidence of obesity-related glomerulopathy has increased tenfold in recent years.

Increased awareness and screening for kidney issues in obese patients is essential.

Metabolische unerwünschte Arzneimittelwirkungen (mUAW) von Psychopharmaka umfassen Gewichtszunahme, gestörte Glukosetoleranz, Diabetes mellitus und Dyslipidämie.

Healthcare providers should monitor metabolic parameters in patients on psychotropic medications.

Ghrelin and leptin are not responsible for the satiating effect of chocolate products.

Practitioners should consider that chocolate may not influence appetite through ghrelin and leptin.

Gastric infusion of milk chocolate elicits a greater increase in cholecystokinin (CCK) compared to oral ingestion of milk chocolate and gastric infusion of non-caloric products.

Infusing chocolate may be more effective for increasing CCK than oral consumption.

The diet of people with limited access to grocery stores was too high in carbohydrates due to their food environment.

Practitioners should consider the impact of food environments on dietary habits in older women.

A one standard deviation higher polygenic score (PS) related to a smaller one-year change in waist circumference adjusted for body mass index (WCadjBMI) in the lifestyle intervention arms at year 1, predicting poorer response among White participants overall.

Practitioners should consider genetic factors when assessing weight loss responses in individuals.

The effect of polygenic risk on change in WCadjBMI with lifestyle intervention is small and not of sufficient magnitude to be clinically significant.

Genetic factors may play a role in weight loss, but their impact may not be significant enough to warrant changes in intervention strategies.

Endoscopic sleeve gastroplasty (ESG) is associated with fewer complications and faster recovery compared to traditional bariatric surgery.

Clinicians can recommend ESG as a safer alternative for patients who are hesitant about traditional surgery.

63.9% of participants remained followed one year after their first clinic visit.

Healthcare providers can expect a significant follow-up rate in obesity management programs.

Participants had 22.16 physician visits per person-year in year one, decreasing to 17.38 by year three.

Healthcare providers should anticipate a decrease in physician visits over time in obesity management.

Nearly half of all patients listed for kidney transplant have obesity, which is associated with increased rates of perioperative complications and graft loss.

Healthcare providers should be aware of the high prevalence of obesity in kidney transplant candidates and its implications for surgery.

Overweight and obesity are significant health challenges addressed globally by the WHO.

Health practitioners should recognize the global significance of overweight and obesity in their practice.

The discussion on appropriate measures for weight reduction is controversial.

Practitioners should be prepared for diverse opinions on weight loss strategies.

Metabolische unerwünschte Arzneimittelwirkungen (mUAW) von Psychopharmaka umfassen Gewichtszunahme, gestörte Glukosetoleranz, Diabetes mellitus und Dyslipidämie.

Healthcare providers should monitor metabolic parameters in patients on psychotropic medications.

Lower body mass index is a significant independent factor for paraspinal muscle atrophy in preoperative lumbar spinal stenosis and lumbar disk herniation patients.

Practitioners should consider body mass index when assessing risk for muscle atrophy in these patients.

Reduced lumbar lordosis angle is a significant independent factor for paraspinal muscle atrophy in preoperative lumbar spinal stenosis and lumbar disk herniation patients.

Practitioners should consider lumbar lordosis angle when assessing risk for muscle atrophy in these patients.

Health care professionals have limited training in obesity care and management.

Practitioners should consider enhancing training programs for obesity management.

Modern pharmacotherapies are fundamental to CKD prevention.

Incorporate modern pharmacotherapies into CKD prevention strategies.

Patients with cardiovascular diseases often show better survival rates with overweight and mild obesity compared to normal body weight.

Healthcare providers should consider the implications of body weight on survival in cardiovascular patients.