Browse the evidence

The experimental group significantly increased their intake of fruits and vegetables and cooking with monounsaturated fat compared to the control group at 1 year.

Group office visits can effectively enhance dietary habits in CAD patients.

Semaglutide 2.4 mg weekly significantly reduces Major Adverse Cardiovascular Events (MACE) in obese patients without type 2 diabetes, independent of the magnitude of weight loss.

If you have obesity (BMI ≥ 27) but no diabetes, weekly semaglutide (2.4 mg) is a proven therapy to significantly lower your risk of heart attack, stroke, and cardiovascular death. This benefit happens through direct protection of your blood vessels and reduction of inflammation, not just by making you lose weight. To get the best results, you must pair the medication with a gradual dose increase to minimize stomach issues, and you must actively engage in resistance training and eat enough protein to prevent muscle loss.

Lifestyle intervention, including diet and exercise, is the cornerstone of T2DM management for women in menopause.

Practitioners should prioritize lifestyle changes in managing T2DM for menopausal women.

Low-volume resistance exercise (140 contractions in 14 days) is effective in attenuating the loss of muscle mass and strength during leg immobilization.

Incorporating low-volume resistance exercise can help maintain muscle mass and strength during periods of immobilization.

Dietary adherence is good when all foods are provided and when participants are highly motivated.

Providing all foods and ensuring participant motivation can enhance adherence to dietary interventions.

Restriction of carbohydrate to 50–130 g per day had beneficial effects on HbA1c in trials up to 6 months.

Low-carbohydrate diets may be beneficial for glycaemic control in the short term for Type 2 diabetes.

A target of 10–15% weight loss is recommended for people with BMI 30–40 kg/m2 or abdominal obesity without complications.

Practitioners should aim for a 10-15% weight loss in this patient group.

For people with BMI 30–40 kg/m2 or abdominal obesity and complications, a weight loss target of 10–15% body weight is recommended.

Practitioners should target a 10-15% weight loss for this patient group.

A weight loss target of > 15% is recommended for those with BMI > 40 kg/m2 and complications.

Practitioners should aim for more than 15% weight loss in this patient group and consider referral to specialists.

If all eligible individuals received medically tailored meals (MTMs), an estimated 1,594,000 hospitalizations could potentially be averted in 1 year.

Healthcare providers should consider the potential benefits of MTMs in reducing hospitalizations for eligible patients.

Current therapy interventions for NAFLD are mainly focused on progressive weight loss through modulation of overall calorie intake with or without specific macronutrient adjustments.

Practitioners should focus on calorie intake modulation for weight loss in NAFLD management.

Other relevant nutritional interventions for NAFLD include food selection and time-restricted eating.

Incorporating food selection and time-restricted eating may benefit NAFLD management.

Liquid meal replacements in weight loss diets lead to a mean reduction in body weight of −2.37 kg (95% CI −3.30 to −1.44).

Incorporating liquid meal replacements can aid in weight loss for individuals with type 2 diabetes.

Liquid meal replacements lead to a mean reduction in HbA1c of −0.43% (−4.7 mmol/mol [−7.2 to −2.1]).

Liquid meal replacements may help improve glycemic control in individuals with type 2 diabetes.

Improving diet, activity level, and medication adherence, as well as controlling tobacco and other substance use, produces measurable, cost-effective improvements in health outcomes.

Practitioners should focus on these behavioral factors to enhance health outcomes.

Sitting for 2.5 hours less each day could result in an extra energy expenditure of 350 kcal/day.

Reducing sitting time may help in weight management strategies.

GLP1-RA treatment is associated with improvements in restrained eating and emotional eating behavior compared with placebo.

GLP1-RAs may help improve eating behaviors in this population.

Roux-en-Y gastric bypass surgery resulted in a greater percentage of excess weight loss compared to medical management, with 66% versus -1.6%.

Practitioners can expect significant weight loss in patients undergoing gastric bypass surgery compared to those managed medically.

Forty-one patients (52.6%) in the surgery group had complete remission of diabetes, while no patient in the control group had remission.

Surgical intervention may lead to significant diabetes remission in eligible patients.

Power training (PT) was associated with an improvement in physical function compared to traditional strength training in older adults.

Practitioners may consider incorporating power training into exercise programs for older adults to enhance physical function.

Power training was associated with an improvement in self-reported physical function compared to traditional strength training.

Incorporating power training may enhance older adults' self-perception of physical function.

Acute post-resistance exercise increases in testosterone (T) and growth hormone (GH) are optimal for maximizing skeletal muscle anabolism and hypertrophy.

Practitioners should consider the importance of T and GH increases in resistance training programs.

Resistance exercise protocols that activate large muscle masses elicit the greatest acute elevations in T and GH.

Design resistance training programs to include large muscle mass exercises for optimal hormonal response.

Participants in the intensive lifestyle intervention (ILI) engaged in significantly more bout-related moderate-to-vigorous-intensity physical activity (MVPA) compared to the Diabetes Support and Education (DSE) group at year 1 (151.0 ± 213.5 vs 87.5 ± 145.1 min·wk, P < 0.0001) and year 4 (102.9 ± 195.6 vs 73.9 ± 267.5 min·wk, P < 0.001).

Implementing intensive lifestyle interventions can significantly increase physical activity levels in older adults with type 2 diabetes.