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Whey protein shows greater rates of MPS compared to soy protein at equivalent doses.

Whey protein may be a better choice for promoting muscle protein synthesis in elderly individuals compared to soy.

Patients with obesity experienced a median weight change of -5% at 6 months and -4% at 18 months after the intervention.

Practitioners can expect significant weight loss in patients with obesity following a multicomponent lifestyle intervention.

Patients reported increased participation in physical activities by +1 day/week after the intervention.

Encouraging physical activity is essential in lifestyle interventions for obesity.

Carbohydrate-restricted diets (CRDs) significantly improved glycemic control, including glucose (SMD = -2.94 mg/dL), insulin (SMD = -8.19 pmol/L), and HOMA-IR (-0.54).

Practitioners may consider CRDs as an effective strategy for improving glycemic control in adults.

LCDs and MCDs showed the most consistent metabolic benefits, particularly with combined fat and protein replacements.

Practitioners should consider LCDs and MCDs with mixed macronutrient replacements for optimal metabolic health.

Weight-reducing anti-diabetic agents and anti-obesity medications can effectively address both obesity and type 2 diabetes mellitus (T2DM).

Practitioners should consider using these combined strategies for better management of patients with obesity and T2DM.

Utilizing a combination of weight-reducing anti-diabetic agents, anti-obesity medications, and surgical procedures can lead to better clinical outcomes in patients with obesity and T2DM.

Combining different treatment modalities may enhance patient outcomes in managing obesity and T2DM.

Nutritional counseling and remote monitoring led to a statistically significant reduction in the average consumption of products containing fats and salt among overweight and obese women.

Practitioners can implement nutritional counseling and remote monitoring to effectively reduce fat and salt intake in overweight and obese patients.

The intervention resulted in a decrease in body weight, body mass index, waist circumference, blood pressure, and lipid metabolism parameters.

Health professionals can expect improvements in key health metrics when implementing similar interventions.

Dietary correction over 6 months contributed to the reduction of risk factors for cardiovascular diseases.

Dietary interventions can be effective in reducing cardiovascular disease risk factors in overweight and obese populations.

Strength training in elderly overweight women exerts positive effects on upper and lower limb strength and also increases cognitive performance.

Incorporating strength training can enhance cognitive function in older women who are overweight.

Weight loss interventions can improve reproductive outcomes in women.

Implementing weight loss strategies may enhance fertility treatment success.

Substitution of LCSBs for sugar-sweetened beverages (SSBs) is associated with a reduction in body weight by −0.47 kg and risk of diabetes (RR, 0.94).

Replacing SSBs with LCSBs may aid in weight loss and reduce diabetes risk.

Substitution of LCSBs for SSBs is associated with reduced cardiovascular mortality (RR, 0.95) and total mortality (RR, 0.96).

Switching from SSBs to LCSBs may contribute to lower cardiovascular and total mortality.

Both Colorado and Alabama participants lost significant amounts of weight after a 16-week intervention (CO 13.2 ± 4.9 kg, AL 12.5 ± 5.6 kg) with no significant difference between the states (P = 0.9315).

Weight loss interventions can be effective in different regions without significant differences in outcomes.

Daily consumption of a protein‐based, multi‐ingredient nutritional supplement resulted in gains in strength (Δ ∑1RM: +14 ± 4 kg, p=0.001) and lean mass (Δ WBLM: +1.2 ± 0.3 kg, p=0.001) independent of exercise in older men.

Practitioners can consider recommending a multi-ingredient nutritional supplement to older men to enhance strength and lean mass.

The multi‐ingredient nutritional supplement enhanced exercise‐mediated improvements in upper body strength compared to placebo after a 12-week exercise training program.

Incorporating a multi-ingredient supplement may optimize strength gains from exercise in older adults.

Resistance training at both longer and shorter mean muscle lengths produces similar hypertrophic effects.

Practitioners can use a variety of muscle lengths in resistance training without significantly affecting hypertrophy outcomes.

Higher weekly set volumes produced a detectable advantage for muscle hypertrophy (1.8 cm²) but not maximal strength (3.48 kg).

Practitioners should consider higher training volumes for promoting muscle growth.

Sugar-sweetened beverage consumption is independently associated with noncommunicable diseases.

Reducing sugar-sweetened beverage consumption may help mitigate the risk of noncommunicable diseases.

Patients on dialysis achieved a mean total body weight loss of 7.8% (SD 6.1) after being prescribed semaglutide.

Semaglutide may be an effective weight loss intervention for patients on dialysis.

48.2% of patients who were ineligible for transplant due to elevated body mass index achieved waitlist activation after successful weight loss.

Successful weight loss with semaglutide can enhance transplant eligibility for patients.

GLP-1RAs promote weight loss and improve metabolic health.

GLP-1RAs can be utilized to aid in weight management and metabolic health improvement.

Phase 2 trials of retatrutide report unprecedented weight reductions comparable to bariatric surgery.

Retatrutide may provide an effective alternative to surgical weight loss methods.