Browse the evidence

Early detection and proper medical management can greatly reduce the likelihood of serious complications from diabetes.

Implement early detection and management protocols to minimize complications in diabetic patients.

The assessment and promotion of physical activity in clinical settings appears to be effective.

Health professionals should incorporate physical activity assessment and promotion in clinical practice.

Seventeen studies demonstrated improvements in physical activity levels as a result of the interventions.

Practitioners can expect to see improvements in patient physical activity levels with appropriate interventions.

Higher protein consumption was more effective for weight stability in both sexes, with better results in obese women.

Practitioners should consider recommending higher protein diets for weight maintenance, especially in obese women.

The reported dietary benefits for weight sustainability should be ascribed to the macronutrient distribution (higher protein diets) rather than to the structured mode of delivery.

Focus on macronutrient distribution, particularly protein intake, for effective weight maintenance strategies.

Cumulative average total moderate-to-vigorous physical activity (MVPA) is inversely associated with progression to chronic kidney disease (CKD), with a hazard ratio (HR) of 0.91 per 100 min/week higher amount.

Increasing moderate-to-vigorous physical activity may help reduce the risk of chronic kidney disease in individuals with type 2 diabetes and obesity.

An increase in total MVPA from baseline to year 4 (≥63.2 min/week) is associated with a 33% lower risk of progression to CKD compared to the largest MVPA reduction (<−198.3 min/week).

Encouraging increases in physical activity can significantly lower the risk of chronic kidney disease in this population.

Increases in MVPA accumulated in bouts of both <10 min and ≥10 min are associated with a lower risk of progression to CKD.

Incorporating both short and longer physical activity bouts can be beneficial for reducing CKD risk.

Participants in the weight loss program experienced a significant reduction in weight of -4.8±2.3 kg.

Weight loss programs can be effective for first responders with obesity.

Participants showed a significant reduction in percent body fat of -3.9±1.7%.

Effective weight loss programs can also lead to reductions in body fat.

The weight loss program is feasible for supporting career firefighters in their weight loss efforts.

Programs utilizing technology and coaching can effectively aid weight loss in first responders.

Low-carbohydrate diets are effective in reversing metabolic syndrome, with 1580 respondents reporting decreased waist circumference and weight, increased energy levels, and decreased hunger.

Practitioners may consider recommending low-carbohydrate diets for patients with metabolic syndrome.

The majority of respondents experienced improvements in laboratory values, including HbA1c, blood glucose measurements, and lipid panel results.

Practitioners can expect metabolic improvements in patients following low-carbohydrate diets.

Physical activity protects against type-2 diabetes through its positive effects on weight management and metabolic pathways involved in glycemic control that are not weight-dependent.

Encouraging physical activity can be a key strategy in diabetes prevention and management.

A promising strategy to increase physical activity is to encourage people to walk more, starting small and increasing gradually over time.

Starting with small walking goals can help individuals increase their physical activity sustainably.

Participants with higher adherence scores for an overall low-carbohydrate diet (LCD) exhibited lower odds of hepatic steatosis (OR = 0.76, 95% CI: 0.61-0.96, p trend = 0.049).

Encouraging adherence to low-carbohydrate diets may reduce the risk of hepatic steatosis.

Replacing 5% of the energy from carbohydrates with total fat and protein is associated with lower steatosis prevalence (OR = 0.91, 95% CI: 0.83-0.99).

Modifying carbohydrate intake by increasing fat and protein may help lower the risk of hepatic steatosis.

Traditional-set structure (TRAD) resulted in significantly greater velocity loss magnitude (g = 1.50) compared to cluster-set structure (CLUS).

Using traditional-set structures may enhance performance metrics like velocity loss during resistance training.

Traditional-set structure (TRAD) showed greater muscle thickness of the proximal pectoralis major (g = -0.34) compared to cluster-set structure (CLUS).

Traditional-set structures may lead to better hypertrophy outcomes in the proximal pectoralis major.

Substitution of low- and no-calorie sweetened beverages (LNCSBs) for sugar-sweetened beverages (SSBs) was associated with a reduction in body weight by 1.06 kg (95% CI, -1.71 to -0.41 kg).

Practitioners may consider recommending LNCSBs as a substitute for SSBs to aid in weight management.

Substituting LNCSBs for SSBs was associated with a reduction in body mass index (BMI) by 0.32 (95% CI, -0.58 to -0.07).

Practitioners may use BMI changes as an additional metric for assessing the effectiveness of LNCSBs in dietary interventions.

The multi-ingredient supplement (SUPP) resulted in a greater increase in lean body mass (LBM) compared to the placebo (PL) after 10 weeks of resistance exercise training (RET) (SUPP: +4.1 ± 1.3 kg, PL: +2.8 ± 1.7 kg, P < 0.05).

Incorporating a high-quality multi-ingredient supplement may enhance muscle gain during resistance training.

The multi-ingredient supplement (SUPP) increased biceps brachii muscle cross-sectional area (CSA) and thickness compared to the placebo (PL) group.

Using a multi-ingredient supplement may specifically enhance upper-body muscle development.

Postintervention weight change averaged -3.7 ± 9.5%, with greater weight loss in the DSE than the ILI group.

Practitioners should note that weight loss outcomes vary significantly between intervention types.