Research
Cellular
Skeletal muscle pyruvate dehydrogenase activation (PDHa) was 29% lower during the FAT-adpt diet compared to the high-CHO diet.
Lower PDHa activation suggests reduced carbohydrate utilization, which may influence performance strategies.
StrongSupportsmedium confidence
Average exercise PDHa values were 29% lower (P<0.05) during the FAT-adpt compared to CHO.
Why this rating
Based on study design from abstract.
Source
Decreased Skeletal Muscle Pyruvate Dehydrogenase Activation During Cycling Following Short-term High-fat Adaptation With Carbohydrate Restoration
Trent Stellingwerff et al. · Medicine & Science in Sports & Exercise · 2005
DOI 10.1097/00005768-200505001-00056
other · n=7Cited 2×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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