Research
Cellular
Obesity, sarcopenia, and heart failure with preserved ejection fraction (HFpEF) are interconnected through the adipokine axis.
Understanding the link between these conditions can guide treatment strategies.
StrongSupportsmedium confidence
Obesity, sarcopenia, and heart failure with preserved ejection fraction (HFpEF) constitute an interconnected clinical triad driven by multisystem mechanisms centered on the adipokine axis.
Why this rating
The abstract summarizes a review of current evidence.
Source
The Adipokine Axis in Heart Failure: Linking Obesity, Sarcopenia and Cardiac Dysfunction in HFpEF
Luka Komić et al. · International Journal of Molecular Sciences · 2026
DOI 10.3390/ijms27020612
reviewCited 2×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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