Research
Cellular
Rifampicin enhances lipolysis and suppresses lipogenesis in adipocytes.
Rifampicin may be useful in promoting fat loss by altering lipid metabolism.
StrongSupportsmedium confidence
rifampicin inhibits 3T3-L1 preadipocyte differentiation and lipid accumulation by suppressing lipogenesis and enhancing lipolysis.
Why this rating
The findings are based on in vitro and in vivo studies.
Source
Rifampicin prevents diet-induced obesity through Sirt6-dependent lipolysis, adipocyte browning and lipogenesis inhibition
Yang Xu et al. · Biomedicine & Pharmacotherapy · 2025
DOI 10.1016/j.biopha.2025.118226
otherCited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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