Research
Cellular
Higher maximum semaglutide dose was associated with lower post-landmark risk of all-cause mortality (RR 0.42, p<0.001) and composite cardiovascular events (RR 0.51, p<0.001).
Practitioners should consider maximizing semaglutide dosage to enhance cardiovascular outcomes.
StrongSupportsmedium confidence
Higher maximum semaglutide dose was associated with... lower post-landmark risk of all-cause mortality (RR 0.42, p<0.001), composite cardiovascular events (death, myocardial infarction, or stroke; RR 0.51, p<0.001).
Why this rating
Based on the analysis of a large cohort of semaglutide-treated individuals.
Source
Semaglutide cardiovascular outcomes align more closely with attained dose than achieved weight loss
Karthik Murugadoss et al. · medRxiv · 2026
DOI 10.64898/2026.04.02.26350077
cohort · n=505874Cited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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