Research
Cellular
Greater achieved weight loss during the landmark period did not show a consistent association with lower post-landmark cardiovascular risk.
Weight loss alone may not be sufficient to reduce cardiovascular risk, emphasizing the importance of medication dosage.
StrongRefutesmedium confidence
In contrast, greater achieved weight loss during the landmark period did not show a consistent monotonic association with lower post-landmark cardiovascular risk.
Why this rating
Based on the analysis of a large cohort.
Source
Semaglutide cardiovascular outcomes align more closely with attained dose than achieved weight loss
Karthik Murugadoss et al. · medRxiv · 2026
DOI 10.64898/2026.04.02.26350077
cohort · n=505874Cited 1×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
Related findings · Cellular
- Athletes aiming to reduce fat mass and preserve FFM should consume protein intakes in the range of ∼1.8-2.7 g kg(-1) d(-1).Strong
- A minimum daily protein intake of ≥1.6 g/kg is necessary to observe significant improvements in muscle mass from whey protein supplementation.Strong
- Most athletes ideally need 1.2 to 2.0 grams/kg of body weight/day of protein, preferably split across 3-4 meals.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →