Research
Cellular
Myozenin-1 protein levels were up-regulated in the low anabolic responders (LO) after 12 weeks of RET.
This suggests that myozenin-1 could be a potential biomarker for assessing anabolic responses to resistance training.
StrongSupportsmedium confidence
POST myofibrillar myozenin-1 protein levels were up-regulated in the LO cluster (LO PRE = 0.96±0.13relative expression units, LO POST = 1.25±0.16; within-group LO increase p=0.025,Cohen's d = 0.691).
Why this rating
The statistical significance of the change in myozenin-1 levels supports the finding.
Source
Peer Review #3 of "Skeletal muscle mitochondrial volume and myozenin-1 protein differences exist between high versus low anabolic responders to resistance training (v0.1)"
Brad J. Schöenfeld · 2018
DOI 10.7287/peerj.5338v0.1/reviews/3
cohort · n=25
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- High anabolic responders (HI) showed greater citrate synthase activity compared to low anabolic responders (LO) after 12 weeks of resistance exercise training (RET) with a significant main effect (HI>LO, p=0.018).Strong
- There were no significant differences in myofibrillar or sarcoplasmic protein concentrations between high and low anabolic responders before or after the 12-week RET program.Strong
Related findings · Cellular
- Athletes aiming to reduce fat mass and preserve FFM should consume protein intakes in the range of ∼1.8-2.7 g kg(-1) d(-1).Strong
- A minimum daily protein intake of ≥1.6 g/kg is necessary to observe significant improvements in muscle mass from whey protein supplementation.Strong
- Most athletes ideally need 1.2 to 2.0 grams/kg of body weight/day of protein, preferably split across 3-4 meals.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →