Research

Cellular

Decrease in sACE2 during a weight loss diet intervention was associated with improvements in fat mass and markers of chronic inflammation.

Weight loss may lead to beneficial changes in inflammation and fat mass through sACE2 modulation.

StrongSupportsmedium confidence
Decrease in sACE2 during a weight loss diet intervention was associated with improvements in metabolic health, fat mass and markers of angiotensin peptide metabolism, vascular injury, renal function, chronic inflammation and oxidative stress.
Nicholas Cauwenberghs et al. · European Heart Journal · 2021

Why this rating

Based on the comprehensive analysis of health markers in a large cohort.

Source

The association of soluble ACE2 change with metabolic health, body composition and proteome dynamics during a weight loss diet intervention: implications for the COVID-19 pandemic

Nicholas Cauwenberghs et al. · European Heart Journal · 2021

DOI 10.1093/eurheartj/ehab724.2636

cohort · n=457
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DOI resolved against Crossref · corpus check 2026-06-10

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