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Cellular

Myofibrillar protein synthesis rates were 36% lower in the immobilized leg compared to the control leg over one week (P<0.001).

Reduced protein synthesis during disuse highlights the importance of maintaining activity to support muscle health.

StrongSupportsmedium confidence
We found that over the one week immobilization period myofibrillar protein synthesis rates were 36 % lower in the immobilized compared with the control leg (P<0.001).
Sean P. Kilroe · 2023

Why this rating

Supported by significant statistical findings.

Source

The impact of short term disuse and dietary protein intake on skeletal muscle mass and protein synthesis rates in humans

Sean P. Kilroe · 2023

DOI 10.26481/dis.20230925sk

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DOI resolved against Crossref · corpus check 2026-06-10

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