Research
Cellular
Basal expression of HSP72 mRNA is lower by 33% in patients with type 2 diabetes compared to age-matched and young control subjects.
Practitioners should consider the reduced HSP72 expression as a potential marker of oxidative stress in diabetic patients.
StrongSupportsmedium confidence
Basal expression of both HSP72 and HO-1 mRNA were lower (P < 0.05) by 33 and 55%, respectively, when comparing diabetic patients with age-matched and young control subjects.
Why this rating
Based on the controlled study design with multiple groups.
Source
Intramuscular Heat Shock Protein 72 and Heme Oxygenase-1 mRNA Are Reduced in Patients With Type 2 Diabetes
Clinton R. Bruce et al. · Diabetes · 2003
DOI 10.2337/diabetes.52.9.2338
cross-sectional · n=21Cited 317×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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