Research
Cellular
HO-1 mRNA expression is increased approximately 70-fold in diabetic patients after the clamp.
The significant increase in HO-1 mRNA suggests a potential compensatory mechanism in response to oxidative stress in diabetes.
StrongSupportsmedium confidence
it was increased (P < 0.05) approximately 70-fold in the diabetic patients after the clamp.
Why this rating
Based on the controlled study design with multiple groups.
Source
Intramuscular Heat Shock Protein 72 and Heme Oxygenase-1 mRNA Are Reduced in Patients With Type 2 Diabetes
Clinton R. Bruce et al. · Diabetes · 2003
DOI 10.2337/diabetes.52.9.2338
cross-sectional · n=21Cited 317×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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