Research
Neural
Higher doses of vitamin D did not improve lower extremity function compared to 24,000 IU.
Increasing vitamin D dosage may not enhance physical performance in older adults.
StrongRefutesmedium confidence
they were not more effective in improving lower extremity function, which did not differ among the treatment groups (P = .26).
Why this rating
Based on the design of a randomized clinical trial.
Source
Monthly High-Dose Vitamin D Treatment for the Prevention of Functional Decline
Heike A. Bischoff‐Ferrari et al. · JAMA Internal Medicine · 2016
DOI 10.1001/jamainternmed.2015.7148
rct · n=200Cited 501×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Higher monthly doses of vitamin D (60,000 IU and 24,000 IU plus calcifediol) were more likely to result in 25-hydroxyvitamin D levels of at least 30 ng/mL compared to 24,000 IU.Strong
- Higher doses of vitamin D (60,000 IU and 24,000 IU plus calcifediol) were associated with an increased risk of falls compared to 24,000 IU.Strong
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