Research
Neural
Higher doses of vitamin D (60,000 IU and 24,000 IU plus calcifediol) were associated with an increased risk of falls compared to 24,000 IU.
Practitioners should be cautious with high-dose vitamin D in older adults due to potential fall risks.
StrongSupportsmedium confidence
the incidence of falls differed significantly among the treatment groups, with higher incidences in the 60,000 IU group (66.9%) and the 24,000 IU plus calcifediol group (66.1%) compared with the 24,000 IU group (47.9%) (P = .048).
Why this rating
Based on the design of a randomized clinical trial.
Source
Monthly High-Dose Vitamin D Treatment for the Prevention of Functional Decline
Heike A. Bischoff‐Ferrari et al. · JAMA Internal Medicine · 2016
rct · n=200Cited 501×
Read the paper This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →