Research
Cellular
Higher monthly doses of vitamin D (60,000 IU and 24,000 IU plus calcifediol) were more likely to result in 25-hydroxyvitamin D levels of at least 30 ng/mL compared to 24,000 IU.
Higher doses of vitamin D may be necessary to achieve adequate serum levels in older adults.
StrongSupportsmedium confidence
Intent-to-treat analyses showed that, while 60,000 IU and 24,000 IU plus calcifediol were more likely than 24,000 IU to result in 25-hydroxyvitamin D levels of at least 30 ng/mL (P = .001).
Why this rating
Based on the design of a randomized clinical trial.
Source
Monthly High-Dose Vitamin D Treatment for the Prevention of Functional Decline
Heike A. Bischoff‐Ferrari et al. · JAMA Internal Medicine · 2016
DOI 10.1001/jamainternmed.2015.7148
rct · n=200Cited 501×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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